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Finally, most prior studies have been limited to single-site interventions, many of which were underpowered and/or limited by selection bias.

A ‘screening log’ of basic demographic information and reasons for not participating in patients deemed ineligible or declined to participate has been recorded.See: The benefits of secondary prevention strategies for coronary heart disease (CHD) targeting lifestyle modification and risk factor management are well established worldwide,1 2 however adoption of these strategies is suboptimal.3 Smoking, inactivity and obesity are prevalent among people with established CHD and control of hypertension and diabetes are often suboptimal. Prior studies revealed that only three-fourths of all hospitalised patients take all medications from their discharge prescriptions by 120 days after discharge.4 Furthermore, less than half of patients hospitalised with acute myocardial infarction (AMI) are adherent to evidence-based medications 1 year later, with the greatest gaps in adherence occurring in the first 6 months after treatment initiation.5–7 In lower-income and middle-income countries (LMICs), including China, which face a growing burden of cardiovascular disease and greater challenges to medication access for secondary prevention, over two-thirds of patients with CHD take no medication.8–10 While high medication costs are a barrier,11 there is also limited time for education and consultation regarding lifestyle and medication management during clinic visits, which tend to be very brief.12 13 Therefore, innovative and cost-effective interventions to enhance adherence are urgently needed.Mobile phones are pervasive and thus can be used to deliver interventions that help people adopt secondary prevention strategies for CHD in LMICs.Results will be disseminated via usual scientific forums including peer-reviewed publications.